MiR-122-5p promotes peritoneal fibrosis in a rat model of peritoneal dialysis by targeting Smad5 to activate Wnt/β-catenin pathway

Peritoneal fibrosis (PF) is the main reason leading to declining efficiency and ultrafiltration failure of peritoneum, which restricts the application of peritoneal dialysis (PD). We aimed to investigate the effects and mechanisms of miR-122-5p on the PF. Sprague-Dawley (SD) rats were infused with g...

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Bibliographic Details
Main Authors: Yirong Liu, Zhihong Ma, Zhenxing Huang, Dongmei Zou, Junbin Li, Ping Feng
Format: Article
Language:English
Published: Taylor & Francis Group 2022-12-01
Series:Renal Failure
Subjects:
Online Access:http://dx.doi.org/10.1080/0886022X.2022.2030360