In- silico evaluation of bioactive compounds from selected medicinal plants from Southern Nigeria against hepatitis C virus genotype 1 RNA-directed RNA polymerase

In- silico evaluation of bioactive compounds from selected medicinal plants from Southern Nigeria against hepatitis C virus genotype 1 RNA-directed RNA polymerase

Background: At the moment, there is no vaccine for the hepatitis C virus (HCV), despite it being more infectious than the hepatitis B virus (HBV) and the human immunodeficiency virus (HIV). Existing drugs based on protease and polymerase inhibitors present adverse clinical outcomes, sparking the sea...

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Bibliographic Details
Main Authors: Clement I. Mboto, Uwem O. Edet, Elizabeth N. Mbim, Wilfred O. Ndifon, Eno E. Ebenso, Henry O. Egharevba, Uwem E. George, Francisca O. Nwaokorie, Samuel.I. Udo
Format: Article
Language:English
Published: Elsevier 2023-11-01
Series:Scientific African
Subjects:
Docking
Bioactive compounds
Medicinal plants
HCV
Genotype 1
Drug target
Online Access:http://www.sciencedirect.com/science/article/pii/S2468227623003745

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http://www.sciencedirect.com/science/article/pii/S2468227623003745

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