Corticosteroids in Sepsis and Septic Shock: A Systematic Review, Pairwise, and Dose-Response Meta-Analysis

OBJECTIVES:. To perform a systematic review and meta-analysis to assess the efficacy and safety of corticosteroids in patients with sepsis. DATA SOURCES:. We searched PubMed, Embase, and the Cochrane Library, up to January 10, 2023. STUDY SELECTION:. We included randomized controlled trials (RCTs) c...

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Main Authors: Tyler Pitre, MD, MA, Katherine Drover, Dipayan Chaudhuri, MD, MSc, Dena Zeraaktkar, PhD, Kusum Menon, MD, MSc, Hayley B. Gershengorn, MD, Namita Jayaprakash, MD, Joanna L. Spencer-Segal, MD, PhD, Stephen M. Pastores, MD, Andrea M. Nei, PharmD, Djillali Annane, MD, PhD, Bram Rochwerg, MD, MSc
Format: Article
Language:English
Published: Wolters Kluwer 2024-01-01
Series:Critical Care Explorations
Online Access:http://journals.lww.com/10.1097/CCE.0000000000001000