Calcium Channel Opening Rather than the Release of ATP Causes the Apoptosis of Osteoblasts Induced by Overloaded Mechanical Stimulation

Calcium Channel Opening Rather than the Release of ATP Causes the Apoptosis of Osteoblasts Induced by Overloaded Mechanical Stimulation

Background: Stress fracture is one of the most common overuse injuries in athletes. Overloaded mechanical stimulation is an important factor affecting stress fractures, but the mechanism is unclear. Methods: MC3T3-E1 cells and a polycaprolactone (PCL) scaffold were co-cultured, and finite element an...

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Bibliographic Details
Main Authors: Lu Liu, Hui Li, Ying Cui, Ruixin Li, Fan Meng, Zi Ye, Xizheng Zhang
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2017-06-01
Series:Cellular Physiology and Biochemistry
Subjects:
Osteoblast
Overloading
Calcium channel
ATP
Cell apoptosis
Online Access:http://www.karger.com/Article/FullText/477592

Internet

http://www.karger.com/Article/FullText/477592

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