A Multisubcellular Compartment Model of AMPA Receptor Trafficking for Neuromodulation of Hebbian Synaptic Plasticity

Neuromodulation can profoundly impact the gain and polarity of postsynaptic changes in Hebbian synaptic plasticity. An emerging pattern observed in multiple central synapses is a pull–push type of control in which activation of receptors coupled to the G-protein Gs promote long-term potentiation (LT...

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Bibliographic Details
Main Authors: Stefan Mihalas, Alvaro Ardiles, Kaiwen He, Adrian Palacios, Alfredo Kirkwood
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Synaptic Neuroscience
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fnsyn.2021.703621/full