The Helix-Loop-Helix motif of human EIF3A regulates translation of proliferative cellular mRNAs.

Improper regulation of translation initiation, a vital checkpoint of protein synthesis in the cell, has been linked to a number of cancers. Overexpression of protein subunits of eukaryotic translation initiation factor 3 (eIF3) is associated with increased translation of mRNAs involved in cell proli...

詳細記述

書誌詳細
主要な著者: Marina P Volegova, Cynthia Hermosillo, Jamie H D Cate
フォーマット: 論文
言語:English
出版事項: Public Library of Science (PLoS) 2023-01-01
シリーズ:PLoS ONE
オンライン・アクセス:https://doi.org/10.1371/journal.pone.0292080