A Functional Variant in the Aquaporin-3 Promoter Modulates Its Expression and Correlates With Resistance to Porcine Epidemic Virus Infection in Porcine Intestinal Epithelial Cells

A Functional Variant in the Aquaporin-3 Promoter Modulates Its Expression and Correlates With Resistance to Porcine Epidemic Virus Infection in Porcine Intestinal Epithelial Cells

Porcine epidemic diarrhea virus (PEDV) causes a highly contagious intestinal disease in neonatal pigs. Aquaporin-3 (AQP3) plays important roles in maintenance of intestinal barrier function and regulation of immune responses. However, the roles of AQP3 in mediating PEDV infection to host cells and t...

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Bibliographic Details
Main Authors: Haifei Wang, Zhenbin Bi, Kaiyu Dai, Pinghua Li, Ruihua Huang, Shenglong Wu, Wenbin Bao
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Microbiology
Subjects:
porcine epidemic diarrhea virus
AQP3
promoter genetic variant
CEBPA
virus resistance
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2022.877644/full

Internet

https://www.frontiersin.org/articles/10.3389/fmicb.2022.877644/full

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