Quantitative analysis of the UDP‐glucuronosyltransferase transcriptome in human tissues

Quantitative analysis of the UDP‐glucuronosyltransferase transcriptome in human tissues

Abstract UDP‐glucuronosyltransferases (UGTs) are phase II drug metabolizing enzymes that play important roles in the detoxification of endogenous and exogenous substrates. The 22 human UGTs belong to four families (UGT1, UGT2, UGT3, and UGT8) and differ in their expression, substrate specificity, UD...

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Bibliographic Details
Main Authors: Lucas Zhou, Abelardo D. Montalvo, Joseph M. Collins, Danxin Wang
Format: Article
Language:English
Published: Wiley 2023-12-01
Series:Pharmacology Research & Perspectives
Subjects:
coexpression
gene expression
splice isoform
transcriptome
UGP‐glucuronosyltransferase (UGT)
Online Access:https://doi.org/10.1002/prp2.1154

Internet

https://doi.org/10.1002/prp2.1154

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