Growth factor and ultrasound-assisted bioreactor synergism for human mesenchymal stem cell chondrogenesis

Ultrasound at 5.0 MHz was noted to be chondro-inductive, with improved SOX-9 gene and COL2A1 protein expression in constructs that allowed for cell-to-cell contact. To achieve tissue-engineered cartilage using macroporous scaffolds, it is hypothesized that a combination of ultrasound at 5.0 MHz and...

Full description

Bibliographic Details
Main Authors: Sanjukta Guha Thakurta, Gaurav Budhiraja, Anuradha Subramanian
Format: Article
Language:English
Published: SAGE Publishing 2015-01-01
Series:Journal of Tissue Engineering
Online Access:https://doi.org/10.1177/2041731414566529