The relationship between health-related quality of life and melancholic depressive symptoms is modified by brain insulin receptor gene network

The relationship between health-related quality of life and melancholic depressive symptoms is modified by brain insulin receptor gene network

Abstract To investigate whether expression-based polygenic risk scores for the insulin receptor gene network (ePRS-IRs) modifiy the association between type of depressive symptoms and health-related quality of life (HRQoL). This cross-sectional study includes 1558 individuals from the Helsinki Birth...

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Bibliographic Details
Main Authors: Jannica S. Selenius, Patricia P. Silveira, Minna Salonen, Hannu Kautiainen, Mikaela von Bonsdorff, Eero Kajantie, Jari Lahti, Johan G. Eriksson, Niko S. Wasenius
Format: Article
Language:English
Published: Nature Portfolio 2021-11-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-00631-w

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https://doi.org/10.1038/s41598-021-00631-w

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