Addressing the batch effect issue for LC/MS metabolomics data in data preprocessing
Abstract With the growth of metabolomics research, more and more studies are conducted on large numbers of samples. Due to technical limitations of the Liquid Chromatography–Mass Spectrometry (LC/MS) platform, samples often need to be processed in multiple batches. Across different batches, we often...
Main Authors: | , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2020-08-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-020-70850-0 |