Construction and Evaluation of Recombinant Adenovirus Candidate Vaccines for Chikungunya Virus

Construction and Evaluation of Recombinant Adenovirus Candidate Vaccines for Chikungunya Virus

Chikungunya virus (CHIKV) is a mosquito-borne virus. The emergence of CHIKV infection has raised global concern, and there is a growing need to develop safe and effective vaccines. Here, adenovirus 5 was used as the vaccine vector to construct recombinant adenoviruses expressing CHIKV E2, E1, and E2...

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Bibliographic Details
Main Authors: Liang Cao, Wei Wang, Wenchao Sun, Jinyong Zhang, Jicheng Han, Changzhan Xie, Zhuo Ha, Yubiao Xie, He Zhang, Ningyi Jin, Huijun Lu
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Viruses
Subjects:
Chikungunya virus
recombinant adenovirus vaccine
glycoproteins
immunogenicity
mice
Online Access:https://www.mdpi.com/1999-4915/14/8/1779

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https://www.mdpi.com/1999-4915/14/8/1779

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