Radiosensitization of orthotopic GIC-driven glioblastoma by doxycycline causes skin damage

Radiosensitization of orthotopic GIC-driven glioblastoma by doxycycline causes skin damage

Abstract Doxycycline (DXC) is a tetracycline antibiotic which has been proposed as a breast cancer radiosensitizer by specifically reducing the expression of the DNA repair enzyme DNA PK in breast cancer initiating cells. Since DXC presents favorable pharmacokinetics properties including the capacit...

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Bibliographic Details
Main Authors: Guido Frosina, Daniela Marubbi, Diana Marcello, Antonio Daga
Format: Article
Language:English
Published: BMC 2019-04-01
Series:Radiation Oncology
Subjects:
glioma animal models
radiosensitization
doxycycline
Online Access:http://link.springer.com/article/10.1186/s13014-019-1266-4

Internet

http://link.springer.com/article/10.1186/s13014-019-1266-4

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