MicroRNA-302a is involved in folate deficiency-induced apoptosis through the AKT-FOXO1-BIM pathway in mouse embryonic stem cells

MicroRNA-302a is involved in folate deficiency-induced apoptosis through the AKT-FOXO1-BIM pathway in mouse embryonic stem cells

Abstract Background Our previous study had shown that microRNA (miR)-302a played a key role in folate deficiency-induced apoptosis in mouse embryonic stem cells. However, details regarding the mechanism remain unclear. Transcription factors (TFs) and miRNAs are two key elements in gene regulation. T...

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Bibliographic Details
Main Authors: Yan Liang, Dingding Cao, Yuanyuan Li, Zhuo Liu, Jianxin Wu
Format: Article
Language:English
Published: BMC 2020-12-01
Series:Nutrition & Metabolism
Subjects:
miR-302a
Akt/FOXO1/Bim pathway
Folate deficiency
Cell apoptosis
Online Access:https://doi.org/10.1186/s12986-020-00530-3

Internet

https://doi.org/10.1186/s12986-020-00530-3

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