Assessment of high resolution melt analysis feasibility for evaluation of beta-globin gene mutations as a reproducible, cost-efficient and fast alternative to the present conventional method

Background: Beta-thalassemia is the most prevalent monogenic disease throughout the world. It was the first genetic disorder nominated for nation-wide prevention programs involving population screening for heterozygotes and prenatal diagnosis (PND) in Iran. Due to the high prevalence of beta-thalass...

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Bibliographic Details
Main Authors: Mahboubeh Ramezanzadeh, Mansour Salehi, Rasoul Salehi
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2016-01-01
Series:Advanced Biomedical Research
Subjects:
Online Access:http://www.advbiores.net/article.asp?issn=2277-9175;year=2016;volume=5;issue=1;spage=71;epage=71;aulast=Ramezanzadeh