S-Adenosylmethionine Decreases Bacterial Translocation, Proinflammatory Cytokines, Oxidative Stress and Apoptosis Markers in Hepatic Ischemia-Reperfusion Injury in Wistar Rats

Hepatic ischemia/reperfusion injury (IRI) can seriously impair liver function. It is initiated by oxidative stress, resulting in inflammation and apoptosis-induced cellular damage. Glutathione (GSH) prevents oxidative stress. S-Adenosylmethionine (SAMet) is a GSH synthesis precursor that avoids the...

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Bibliographic Details
Main Authors: Sergio Valdés, Sergio D. Paredes, Carmen García Carreras, Pilar Zuluaga, Lisa Rancan, Beatriz Linillos-Pradillo, Javier Arias-Díaz, Elena Vara
Format: Article
Language:English
Published: MDPI AG 2023-07-01
Series:Antioxidants
Subjects:
Online Access:https://www.mdpi.com/2076-3921/12/8/1539