Correlative proteomics identify the key roles of stress tolerance strategies in Acinetobacter baumannii in response to polymyxin and human macrophages.

The opportunistic pathogen Acinetobacter baumannii possesses stress tolerance strategies against host innate immunity and antibiotic killing. However, how the host-pathogen-antibiotic interaction affects the overall molecular regulation of bacterial pathogenesis and host response remains unexplored....

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Bibliographic Details
Main Authors: Zhi Ying Kho, Mohammad A K Azad, Mei-Ling Han, Yan Zhu, Cheng Huang, Ralf B Schittenhelm, Thomas Naderer, Tony Velkov, Joel Selkrig, Qi Tony Zhou, Jian Li
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-03-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1010308