The role of pattern-recognition receptors in Graft-versus-host disease and Graft-versus-leukemia after allogeneic stem cell transplantation

The role of pattern-recognition receptors in Graft-versus-host disease and Graft-versus-leukemia after allogeneic stem cell transplantation

Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is the only treatment with curative potential for certain aggressive hematopoietic malignancies. Its success is limited by acute graft-versus-host disease (GVHD), a life-threatening complication that occurs when alloreactive donor T cell...

Full description

Bibliographic Details
Main Authors: Simon eHeidegger, Marcel R. M. van den Brink, Tobias eHaas, Hendrik ePoeck
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-07-01
Series:Frontiers in Immunology
Subjects:
microbiota
Pattern-recognition receptors
graft-versus-host disease
allogenic hematopoietic stem cell transplantation
inflammsome
danger molecules
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2014.00337/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fimmu.2014.00337/full

Similar Items