Revisiting the Role of the CXCL13/CXCR5-Associated Immune Axis in Melanoma: Potential Implications for Anti-PD-1-Related Biomarker Research

CXCL13 is a potent chemoattractant cytokine that promotes the migration of cells expressing its cognate receptor, CXCR5. Accordingly, T follicular helper cells and B cells migrate towards B cell follicles in lymph nodes, where the resulting spatial proximity promotes B cell/T cell interaction and an...

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Bibliographic Details
Main Authors: Magdalena Hoellwerth, Peter Koelblinger, Roland Lang, Andrea Harrer
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Life
Subjects:
Online Access:https://www.mdpi.com/2075-1729/13/2/553