Recruitment of the Histone Variant MacroH2A1 to the Pericentric Region Occurs upon Chromatin Relaxation and Is Responsible for Major Satellite Transcriptional Regulation

Recruitment of the Histone Variant MacroH2A1 to the Pericentric Region Occurs upon Chromatin Relaxation and Is Responsible for Major Satellite Transcriptional Regulation

Heterochromatin formation plays a pivotal role in regulating chromatin organization and influences nuclear architecture and genome stability and expression. Amongst the locations where heterochromatin is found, the pericentric regions have the capability to attract the histone variant macroH2A1. How...

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Bibliographic Details
Main Authors: Ludmila Recoules, Nicolas Tanguy Le Gac, Fatima Moutahir, Kerstin Bystricky, Anne-Claire Lavigne
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:Cells
Subjects:
pericentromeric regions
histone variant
macroH2A1
chromatin decondensation
Online Access:https://www.mdpi.com/2073-4409/12/17/2175

Internet

https://www.mdpi.com/2073-4409/12/17/2175

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