NMR indicates the N-termini of PSGL1 and CCR7 bind competitively to the chemokine CCL21

NMR indicates the N-termini of PSGL1 and CCR7 bind competitively to the chemokine CCL21

Chemokines are from a family of secreted cytokines that direct the trafficking of immune cells to coordinate immune responses. Chemokines are involved in numerous disease states, including responding to infections, autoimmune disorders, and cancer metastasis. Ther are chemokines, like CCL21, that si...

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Bibliographic Details
Main Authors: Robin N. Witt, Kaileigh S. Nickel, John R. Binns, Alexander M. Gray, Alyssa M. Hintz, Noah F. Kofron, Steven F. Steigleder, Francis C. Peterson, Christopher T. Veldkamp
Format: Article
Language:English
Published: Elsevier 2023-09-01
Series:Biochemistry and Biophysics Reports
Subjects:
Chemokines
CCL21
CCR7
Metastasis
NMR
PSGL1
Online Access:http://www.sciencedirect.com/science/article/pii/S240558082300105X

Internet

http://www.sciencedirect.com/science/article/pii/S240558082300105X

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