The GTPase Nog1 co-ordinates the assembly, maturation and quality control of distant ribosomal functional centers

The GTPase Nog1 co-ordinates the assembly, maturation and quality control of distant ribosomal functional centers

Eukaryotic ribosome precursors acquire translation competence in the cytoplasm through stepwise release of bound assembly factors, and proofreading of their functional centers. In case of the pre-60S, these steps include removal of placeholders Rlp24, Arx1 and Mrt4 that prevent premature loading of...

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Bibliographic Details
Main Authors: Purnima Klingauf-Nerurkar, Ludovic C Gillet, Daniela Portugal-Calisto, Michaela Oborská-Oplová, Martin Jäger, Olga T Schubert, Agnese Pisano, Cohue Peña, Sanjana Rao, Martin Altvater, Yiming Chang, Ruedi Aebersold, Vikram G Panse
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2020-01-01
Series:eLife
Subjects:
ribosome assembly
ribosome quality control
cytoplasmic maturation
Online Access:https://elifesciences.org/articles/52474

Internet

https://elifesciences.org/articles/52474

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