NMR-Based Metabolomic Analysis of Plasma in Patients with Adult Congenital Heart Disease and Associated Pulmonary Arterial Hypertension: A Pilot Study

NMR-Based Metabolomic Analysis of Plasma in Patients with Adult Congenital Heart Disease and Associated Pulmonary Arterial Hypertension: A Pilot Study

Patients with unrepaired congenital heart disease (CHD) are prone to pulmonary arterial hypertension (PAH). The ovine pulmonary arterial smooth muscle cells exposed to increased pulmonary blood flow (PBF) exhibited hyperproliferation and metabolic alterations, but the metabolic disorders of patients...

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Bibliographic Details
Main Authors: Beizhu Xu, Caihua Huang, Caojin Zhang, Donghai Lin, Weifeng Wu
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Metabolites
Subjects:
pulmonary arterial hypertension
congenital heart disease
<sup>1</sup>H-NMR
metabolomics
biomarker
metabolite
Online Access:https://www.mdpi.com/2218-1989/12/9/845

Internet

https://www.mdpi.com/2218-1989/12/9/845

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