α/β-Peptides as Nanomolar Triggers of Lipid Raft-Mediated Endocytosis through GM1 Ganglioside Recognition

α/β-Peptides as Nanomolar Triggers of Lipid Raft-Mediated Endocytosis through GM1 Ganglioside Recognition

Cell delivery of therapeutic macromolecules and nanoparticles is a critical drug development challenge. Translocation through lipid raft-mediated endocytic mechanisms is being sought, as it can avoid rapid lysosomal degradation. Here, we present a set of short α/β-peptide tags with high affinity to...

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Bibliographic Details
Main Authors: Anasztázia Hetényi, Enikő Szabó, Norbert Imre, Kaushik Nath Bhaumik, Attila Tököli, Tamás Füzesi, Réka Hollandi, Peter Horvath, Ágnes Czibula, Éva Monostori, Mária A. Deli, Tamás A. Martinek
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:Pharmaceutics
Subjects:
cell delivery
glycan recognition
alpha-beta peptide
endocytosis
immunoglobulin
Online Access:https://www.mdpi.com/1999-4923/14/3/580

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https://www.mdpi.com/1999-4923/14/3/580

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