Blood neurofilament light chain as a biomarker for monitoring and predicting paclitaxel-induced peripheral neuropathy in patients with gynecological cancers

Blood neurofilament light chain as a biomarker for monitoring and predicting paclitaxel-induced peripheral neuropathy in patients with gynecological cancers

ObjectiveWe aimed to evaluate the potential of serum neurofilament light chain (sNfL) and serum brain-derived neurotrophic factor (sBDNF) as reliable biomarkers for paclitaxel-induced peripheral neuropathy (PIPN).MethodsForty-eight patients with gynecologic cancer scheduled to undergo six cycles of...

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Bibliographic Details
Main Authors: Su-Hyun Kim, Ki Hoon Kim, Jae-Won Hyun, Ji Hyun Kim, Sang-Soo Seo, Ho Jin Kim, Sang-Yoon Park, Myong Cheol Lim
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Oncology
Subjects:
paclitaxel
neuropathy
neurofilament light (NfL)
gynecological cancer
chemotherapy induced peripheral neuropathy
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.942960/full

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https://www.frontiersin.org/articles/10.3389/fonc.2022.942960/full

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