Novel Double Factor PGT strategy analyzing blastocyst stage embryos in a single NGS procedure.

In families at risk from monogenic diseases affected offspring, it is fundamental the development of a suitable Double Factor Preimplantation Genetic Testing (DF-PGT) method for both single-gene analysis and chromosome complement screening. Aneuploidy is not only a major issue in advanced-maternal-a...

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Bibliographic Details
Main Authors: Javier Del Rey, Francisco Vidal, Lorena Ramírez, Nina Borràs, Irene Corrales, Iris Garcia, Olga Martinez-Pasarell, Silvia F Fernandez, Raquel Garcia-Cruz, Aïda Pujol, Alberto Plaja, Itziar Salaverria, Maria Oliver-Bonet, Jordi Benet, Joaquima Navarro
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC6192598?pdf=render