Effects of intermittent T-cell cluster disaggregation on proliferative capacity and checkpoint marker expression

Background/aim: T-cell immunotherapies are rapidly gaining grounds in clinical success. Presently, there is first-to-market knowledge on the translation of research scale methods to clinical and commercial scales. Improved understanding can lead to more consistent and efficient production, scaling,...

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Bibliographic Details
Main Authors: Matthew Li, Ling-Yee Chin, Sykuri Shukor, Alfred G. Tamayo, Marcela V. Maus, Biju Parekkadan
Format: Article
Language:English
Published: Taylor & Francis Group 2019-04-01
Series:Autoimmunity
Subjects:
Online Access:http://dx.doi.org/10.1080/08916934.2019.1630064