Redox balance influences differentiation status of neuroblastoma in the presence of all-trans retinoic acid

Neuroblastoma is the most common extra-cranial solid tumor in childhood; and patients in stage IV of the disease have a high propensity for tumor recurrence. Retinoid therapy has been utilized as a means to induce differentiation of tumor cells and to inhibit relapse. In this study, the expression o...

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Bibliographic Details
Main Authors: Anne M. Silvis, Michael L. McCormick, Douglas R. Spitz, Kinsley K. Kiningham
Format: Article
Language:English
Published: Elsevier 2016-04-01
Series:Redox Biology
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231715300124