Isobavachalcone From Cullen corylifolium Presents Significant Antibacterial Activity Against Clostridium difficile Through Disruption of the Cell Membrane

Isobavachalcone From Cullen corylifolium Presents Significant Antibacterial Activity Against Clostridium difficile Through Disruption of the Cell Membrane

Background:Clostridium difficile infection (CDI) has been widely reported in human and animals around the world over the past few decades. The high relapse rate and increasing drug resistance of CDI make the discovery of new agents against C. difficile fairly urgent. This study aims to investigate t...

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Bibliographic Details
Main Authors: Xi-Wang Liu, Ya-Jun Yang, Zhe Qin, Shi-Hong Li, Li-Xia Bai, Wen-Bo Ge, Jian-Yong Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Pharmacology
Subjects:
Clostridium difficile
psoraleae fructus
antibacterial activity
isobavachalcone
cell membrane integrity
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.914188/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2022.914188/full

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