Effect of C-reactive protein deficiency on insulin resistance reversal in rats with polycystic ovary syndrome through augmented leptin action

Abstract Background C-reactive protein(CRP), is an inflammatory marker that weaken leptin bioavailability and insulin sensitivity to disturb energy and glucose metabolism. Polycystic ovary syndrome (PCOS) exhibit a metabolic component consisting of higher plasma CRP levels, hyperinsulinemic and hype...

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Bibliographic Details
Main Authors: Ke Li, Lingling Hu, Xinrun Li, Zhibin Yuan, Jia He, Dongfang Liu, Gangyi Yang, Lei Yuan
Format: Article
Language:English
Published: BMC 2023-09-01
Series:Diabetology & Metabolic Syndrome
Subjects:
Online Access:https://doi.org/10.1186/s13098-023-01155-1