Potential molecular mechanism in self-renewal is associated with miRNA dysregulation in sacral chordoma – A next-generation RNA sequencing study

Potential molecular mechanism in self-renewal is associated with miRNA dysregulation in sacral chordoma – A next-generation RNA sequencing study

Background: Chordoma, the most frequent malignant primary spinal neoplasm, characterized by a high rate of recurrence, is an orphan disease where the clarification of the molecular oncogenesis would be crucial to developing new, effective therapies. Dysregulated expression of non-coding RNAs, especi...

Full description

Bibliographic Details
Main Authors: Arpad Bozsodi, Beata Scholtz, Gergo Papp, Zoltan Sapi, Adam Biczo, Peter Pal Varga, Aron Lazary
Format: Article
Language:English
Published: Elsevier 2022-08-01
Series:Heliyon
Subjects:
Chordoma
Next-generation sequencing
miRNA
mRNA
Transcriptome profile
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844022015158

Internet

http://www.sciencedirect.com/science/article/pii/S2405844022015158

Similar Items