JAK2-V617F Mutation and Philadelphia Positive Chronic Myeloid Leukemia

JAK2-V617F Mutation and Philadelphia Positive Chronic Myeloid Leukemia

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JAK2 is a tyrosine kinase that plays an important role in the signaling pathways of many hematopoietic growth factor receptors. A single acquired point mutation – V617F – in JAK2 occurs in the great majority of patients with polycythemia vera (PV) and approximately half of the patients with idiopath...

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Bibliographic Details
Main Authors: Fatemeh Nadali, Sh Ferdowsi, P Karimzadeh, Bahram Chahardouli, N Einollahi, SA Mousavi, Babak Bahar, H Dargahi, Kamran Alimoghaddam, Ardeshir Ghavamzadeh, SH Ghaffari
Format: Article
Language:English
Published: Tehran University of Medical Sciences 2009-12-01
Series:International Journal of Hematology-Oncology and Stem Cell Research
Subjects:
JAK2V617F mutation
BCR-ABL translocation
ASO-PCR
ARMS-PCR
Online Access:https://ijhoscr.tums.ac.ir/index.php/ijhoscr/article/view/230

Internet

https://ijhoscr.tums.ac.ir/index.php/ijhoscr/article/view/230

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