Generation of vascularized brain organoids to study neurovascular interactions

Generation of vascularized brain organoids to study neurovascular interactions

Brain organoids have been used to recapitulate the processes of brain development and related diseases. However, the lack of vasculatures, which regulate neurogenesis and brain disorders, limits the utility of brain organoids. In this study, we induced vessel and brain organoids, respectively, and t...

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Bibliographic Details
Main Authors: Xin-Yao Sun, Xiang-Chun Ju, Yang Li, Peng-Ming Zeng, Jian Wu, Ying-Ying Zhou, Li-Bing Shen, Jian Dong, Yue-Jun Chen, Zhen-Ge Luo
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2022-05-01
Series:eLife
Subjects:
brain organoid
brain vasculature
neural progenitors
blood-brain-barrier
microglia
Online Access:https://elifesciences.org/articles/76707

Internet

https://elifesciences.org/articles/76707

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