eIF4E phosphorylation mediated LPS induced depressive-like behaviors via ameliorated neuroinflammation and dendritic loss

Abstract The translational defect has emerged as a common feature of neurological disorders. Studies have suggested that alterations between opposing and balanced synaptic protein synthesis and turnover processes could lead to synaptic abnormalities, followed by depressive symptoms. Further studies...

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Bibliographic Details
Main Authors: Qichao Gong, Weifen Li, Tahir Ali, Yue Hu, Shengnan Mou, Zizhen Liu, Chengyou Zheng, Ruyan Gao, Axiang Li, Tao Li, Ningning Li, Zhijian Yu, Shupeng Li
Format: Article
Language:English
Published: Nature Publishing Group 2023-11-01
Series:Translational Psychiatry
Online Access:https://doi.org/10.1038/s41398-023-02646-5