Arachidonic acid-derived lipid mediators in multiple sclerosis pathogenesis: fueling or dampening disease progression?

Arachidonic acid-derived lipid mediators in multiple sclerosis pathogenesis: fueling or dampening disease progression?

Abstract Background Multiple sclerosis (MS) is a chronic autoimmune disease of the central nervous system (CNS), characterized by neuroinflammation, demyelination, and neurodegeneration. Considering the increasing prevalence among young adults worldwide and the disabling phenotype of the disease, a...

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Bibliographic Details
Main Authors: Jelle Y. Broos, Rianne T. M. van der Burgt, Julia Konings, Merel Rijnsburger, Oliver Werz, Helga E. de Vries, Martin Giera, Gijs Kooij
Format: Article
Language:English
Published: BMC 2024-01-01
Series:Journal of Neuroinflammation
Subjects:
Multiple sclerosis
Arachidonic acid
Prostanoids
Leukotrienes
Inflammation
Demyelination
Online Access:https://doi.org/10.1186/s12974-023-02981-w

Internet

https://doi.org/10.1186/s12974-023-02981-w

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