A gene-phenotype network for the laboratory mouse and its implications for systematic phenotyping.

The laboratory mouse is the pre-eminent model organism for the dissection of human disease pathways. With the advent of a comprehensive panel of gene knockouts, projects to characterise the phenotypes of all knockout lines are being initiated. The range of genotype-phenotype associations can be repr...

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Bibliographic Details
Main Authors: Octavio Espinosa, John M Hancock
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3098258?pdf=render