Spo0A differentially regulates toxin production in evolutionarily diverse strains of Clostridium difficile.

Clostridium difficile is an important pathogen of humans and animals, representing a significant global healthcare problem. The last decade has seen the emergence of epidemic BI/NAP1/027 and ribotype 078 isolates, associated with the onset of more severe disease and higher rates of morbidity and mor...

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Bibliographic Details
Main Authors: Kate E Mackin, Glen P Carter, Pauline Howarth, Julian I Rood, Dena Lyras
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24236153/pdf/?tool=EBI