Mahalanobis distance, a novel statistical proxy of homeostasis loss is longitudinally associated with risk of type 2 diabetes

Mahalanobis distance, a novel statistical proxy of homeostasis loss is longitudinally associated with risk of type 2 diabetes

Background: The potential role of individual plasma biomarkers in the pathogenesis of type 2 diabetes (T2D) has been broadly studied, but the impact of biomarkers interaction remains underexplored. Recently, the Mahalanobis distance (MD) of plasma biomarkers has been proposed as a proxy of physiolog...

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Bibliographic Details
Main Authors: Jose L. Flores-Guerrero, Marco A. Grzegorczyk, Margery A. Connelly, Erwin Garcia, Gerjan Navis, Robin P.F. Dullaart, Stephan J.L. Bakker
Format: Article
Language:English
Published: Elsevier 2021-09-01
Series:EBioMedicine
Subjects:
Type 2 diabetes
Mahalanobis distance
Homeostasis
Dysregulation
Biomarkers
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396421003431

Internet

http://www.sciencedirect.com/science/article/pii/S2352396421003431

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