Fcα Receptor-1-Activated Monocytes Promote B Lymphocyte Migration and IgA Isotype Switching

Fcα Receptor-1-Activated Monocytes Promote B Lymphocyte Migration and IgA Isotype Switching

Patients with inflammatory bowel disease (IBD) produce enhanced immunoglobulin A (IgA) against the microbiota compared to healthy individuals, which has been correlated with disease severity. Since IgA complexes can potently activate myeloid cells via the IgA receptor FcαRI (CD89), excessive IgA pro...

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Bibliographic Details
Main Authors: Amélie V. Bos, Melissa M. J. van Gool, Annelot C. Breedveld, Richard van der Mast, Casper Marsman, Gerd Bouma, Mark A. van de Wiel, S. Marieke van Ham, Reina E. Mebius, Marjolein van Egmond
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:International Journal of Molecular Sciences
Subjects:
immunoglobulin A
IgA
CD89
FcαRI
myeloid cells
monocytes
Online Access:https://www.mdpi.com/1422-0067/23/19/11132

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https://www.mdpi.com/1422-0067/23/19/11132

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