Scaffold Geometry-Imposed Anisotropic Mechanical Loading Guides the Evolution of the Mechanical State of Engineered Cardiovascular Tissues in vitro

Cardiovascular tissue engineering is a promising approach to develop grafts that, in contrast to current replacement grafts, have the capacity to grow and remodel like native tissues. This approach largely depends on cell-driven tissue growth and remodeling, which are highly complex processes that a...

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Bibliographic Details
Main Authors: L. H. L. Hermans, M. A. J. Van Kelle, P. J. A. Oomen, R .G. P. Lopata, S. Loerakker, C. V. C. Bouten
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-02-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2022.796452/full