Environmentally relevant concentration PFNA promotes degradation of SMAD7 to drive progression of ovarian cancer via TGF-β/SMADs signaling pathway

Environmentally relevant concentration PFNA promotes degradation of SMAD7 to drive progression of ovarian cancer via TGF-β/SMADs signaling pathway

Perfluorononanoic acid (PFNA), an acknowledged environmental endocrine disruptor, is increasingly utilized as a substitute for perfluorooctanesulfonic acid (PFOS) and perfluorooctanoic acid (PFOA). Despite its growing use, limited research has been conducted to investigate its potential impact on tu...

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Bibliographic Details
Main Authors: Jiamin Zhong, Lihuan Zhang, Kelie Chen, Xiaoyu Yuan, Zhenyan Cui, Song Tang, Fang Zheng, Ying Li, Paul Héroux, Yihua Wu, Dajing Xia
Format: Article
Language:English
Published: Elsevier 2024-10-01
Series:Ecotoxicology and Environmental Safety
Subjects:
PFNA
Ovarian cancer
EMT
SMAD7
TGF-β/SMADs signaling pathway
Online Access:http://www.sciencedirect.com/science/article/pii/S0147651324009837

Internet

http://www.sciencedirect.com/science/article/pii/S0147651324009837

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