Molecular correlates of vaccine-induced protection against typhoid fever

Molecular correlates of vaccine-induced protection against typhoid fever

BACKGROUND Typhoid fever is caused by the Gram-negative bacterium Salmonella enterica serovar Typhi and poses a substantial public health burden worldwide. Vaccines have been developed based on the surface Vi-capsular polysaccharide of S. Typhi; these include a plain-polysaccharide-based vaccine, Vi...

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Bibliographic Details
Main Authors: Henderson Zhu, Irina Chelysheva, Deborah L. Cross, Luke Blackwell, Celina Jin, Malick M. Gibani, Elizabeth Jones, Jennifer Hill, Johannes Trück, Dominic F. Kelly, Christoph J. Blohmke, Andrew J. Pollard, Daniel O’Connor
Format: Article
Language:English
Published: American Society for Clinical Investigation 2023-08-01
Series:The Journal of Clinical Investigation
Subjects:
Vaccines
Online Access:https://doi.org/10.1172/JCI169676

Internet

https://doi.org/10.1172/JCI169676

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