From the regulatory mechanism of TFEB to its therapeutic implications

From the regulatory mechanism of TFEB to its therapeutic implications

Abstract Transcription factor EB (TFEB), known as a major transcriptional regulator of the autophagy-lysosomal pathway, regulates target gene expression by binding to coordinated lysosomal expression and regulation (CLEAR) elements. TFEB are regulated by multiple links, such as transcriptional regul...

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Bibliographic Details
Main Authors: Huixia Chen, Siqiao Gong, Hongyong Zhang, Yongming Chen, Yonghan Liu, Junfeng Hao, Huafeng Liu, Xiaoyu Li
Format: Article
Language:English
Published: Nature Publishing Group 2024-02-01
Series:Cell Death Discovery
Online Access:https://doi.org/10.1038/s41420-024-01850-6

Internet

https://doi.org/10.1038/s41420-024-01850-6

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