Functional interactomes of the Ebola virus polymerase identified by proximity proteomics in the context of viral replication

Functional interactomes of the Ebola virus polymerase identified by proximity proteomics in the context of viral replication

Summary: Ebola virus (EBOV) critically depends on the viral polymerase to replicate and transcribe the viral RNA genome in the cytoplasm of host cells, where cellular factors can antagonize or facilitate the virus life cycle. Here we leverage proximity proteomics and conduct a small interfering RNA...

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Bibliographic Details
Main Authors: Jingru Fang, Colette Pietzsch, George Tsaprailis, Gogce Crynen, Kelvin Frank Cho, Alice Y. Ting, Alexander Bukreyev, Juan Carlos de la Torre, Erica Ollmann Saphire
Format: Article
Language:English
Published: Elsevier 2022-03-01
Series:Cell Reports
Subjects:
CP: Microbiology
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124722002856

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http://www.sciencedirect.com/science/article/pii/S2211124722002856

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