Functional interactomes of the Ebola virus polymerase identified by proximity proteomics in the context of viral replication

Summary: Ebola virus (EBOV) critically depends on the viral polymerase to replicate and transcribe the viral RNA genome in the cytoplasm of host cells, where cellular factors can antagonize or facilitate the virus life cycle. Here we leverage proximity proteomics and conduct a small interfering RNA...

पूर्ण विवरण

ग्रंथसूची विवरण
मुख्य लेखकों: Jingru Fang, Colette Pietzsch, George Tsaprailis, Gogce Crynen, Kelvin Frank Cho, Alice Y. Ting, Alexander Bukreyev, Juan Carlos de la Torre, Erica Ollmann Saphire
स्वरूप: लेख
भाषा:English
प्रकाशित: Elsevier 2022-03-01
श्रृंखला:Cell Reports
विषय:
ऑनलाइन पहुंच:http://www.sciencedirect.com/science/article/pii/S2211124722002856