Osthole induces necroptosis via ROS overproduction in glioma cells

Glioma is a common primary malignant tumor that has a poor prognosis and often develops drug resistance. The coumarin derivative osthole has previously been reported to induce cancer cell apoptosis. Recently, we found that it could also trigger glioma cell necroptosis, a type of cell death that is u...

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Bibliographic Details
Main Authors: Mengjie Huangfu, Riming Wei, Juan Wang, Jianli Qin, Dan Yu, Xiao Guan, Xumei Li, Minglei Fu, Haiping Liu, Xu Chen
Format: Article
Language:English
Published: Wiley 2021-02-01
Series:FEBS Open Bio
Subjects:
Online Access:https://doi.org/10.1002/2211-5463.13069