CometAnalyser: A user-friendly, open-source deep-learning microscopy tool for quantitative comet assay analysis

CometAnalyser: A user-friendly, open-source deep-learning microscopy tool for quantitative comet assay analysis

Comet assay provides an easy solution to estimate DNA damage in single cells through microscopy assessment. It is widely used in the analysis of genotoxic damages induced by radiotherapy or chemotherapeutic agents. DNA damage is quantified at the single-cell level by computing the displacement betwe...

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Bibliographic Details
Main Authors: Attila Beleon, Sara Pignatta, Chiara Arienti, Antonella Carbonaro, Peter Horvath, Giovanni Martinelli, Gastone Castellani, Anna Tesei, Filippo Piccinini
Format: Article
Language:English
Published: Elsevier 2022-01-01
Series:Computational and Structural Biotechnology Journal
Subjects:
Microscopy
Oncology
Comet assay
Silver and fluorescence staining
Quantitative analysis
Deep learning
Online Access:http://www.sciencedirect.com/science/article/pii/S2001037022003336

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http://www.sciencedirect.com/science/article/pii/S2001037022003336

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