Applicability of DNA pools on 500 K SNP microarrays for cost-effective initial screens in genomewide association studies

<p>Abstract</p> <p>Background</p> <p>Genetic influences underpinning complex traits are thought to involve multiple quantitative trait loci (QTLs) of small effect size. Detection of such QTL associations requires systematic screening of large numbers of DNA markers with...

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Bibliographic Details
Main Authors: Schalkwyk Leonard C, Butcher Lee M, Docherty Sophia J, Plomin Robert
Format: Article
Language:English
Published: BMC 2007-07-01
Series:BMC Genomics
Online Access:http://www.biomedcentral.com/1471-2164/8/214