Monocyte exosomes stimulate the osteogenic gene expression of mesenchymal stem cells.

Inflammation and regeneration at the implant-bone interface are intimately coupled via cell-cell communication. In contrast to the prevailing view that monocytes/macrophages orchestrate mesenchymal stem cells (MSCs) and progenitor cells via the secretion of soluble factors, we examined whether commu...

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Bibliographic Details
Main Authors: Karin Ekström, Omar Omar, Cecilia Granéli, Xiaoqin Wang, Forugh Vazirisani, Peter Thomsen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3776724?pdf=render