Serine metabolism is crucial for cGAS-STING signaling and viral defense control in the gut

Serine metabolism is crucial for cGAS-STING signaling and viral defense control in the gut

Summary: Inflammatory bowel diseases are characterized by the chronic relapsing inflammation of the gastrointestinal tract. While the molecular causality between endoplasmic reticulum (ER) stress and intestinal inflammation is widely accepted, the metabolic consequences of chronic ER stress on the p...

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Bibliographic Details
Main Authors: Björn Becker, Felix Wottawa, Mohamed Bakr, Eric Koncina, Lisa Mayr, Julia Kugler, Guang Yang, Samuel J. Windross, Laura Neises, Neha Mishra, Danielle Harris, Florian Tran, Lina Welz, Julian Schwärzler, Zoltán Bánki, Stephanie T. Stengel, Go Ito, Christina Krötz, Olivia I. Coleman, Christian Jaeger, Dirk Haller, Søren R. Paludan, Richard Blumberg, Arthur Kaser, Luka Cicin-Sain, Stefan Schreiber, Timon E. Adolph, Elisabeth Letellier, Philip Rosenstiel, Johannes Meiser, Konrad Aden
Format: Article
Language:English
Published: Elsevier 2024-03-01
Series:iScience
Subjects:
Virology
Microbial metabolism
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004224003948

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http://www.sciencedirect.com/science/article/pii/S2589004224003948

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