Effect of noradrenaline on propofol-induced mitochondrial dysfunction in human skeletal muscle cells

Effect of noradrenaline on propofol-induced mitochondrial dysfunction in human skeletal muscle cells

Abstract Background Mitochondrial dysfunction is a hallmark of both critical illness and propofol infusion syndrome and its severity seems to be proportional to the doses of noradrenaline, which patients are receiving. We comprehensively studied the effects of noradrenaline on cellular bioenergetics...

Full description

Bibliographic Details
Main Authors: Adéla Krajčová, Christine Skagen, Valér Džupa, Tomáš Urban, Arild C. Rustan, Kateřina Jiroutková, Bohumil Bakalář, G. Hege Thoresen, František Duška
Format: Article
Language:English
Published: SpringerOpen 2022-11-01
Series:Intensive Care Medicine Experimental
Subjects:
Propofol infusion syndrome
Noradrenaline
Mitochondrial dysfunction
Skeletal muscle
Critical illness
Online Access:https://doi.org/10.1186/s40635-022-00474-3

Internet

https://doi.org/10.1186/s40635-022-00474-3

Similar Items